DEHYDROEVODIAMINE 去氢吴茱萸碱
Dehydroevodiamine
CAS: 67909-49-3
Molecular Formula: C19H15N3O
DEHYDROEVODIAMINE 去氢吴茱萸碱 - Names and Identifiers
| Name | Dehydroevodiamine |
| Synonyms | dehydrovodiamine Dehydroevodiamine |
| CAS | 67909-49-3 |
| EINECS | 200-258-5 |
DEHYDROEVODIAMINE 去氢吴茱萸碱 - Physico-chemical Properties
| Molecular Formula | C19H15N3O |
| Molar Mass | 301.35 |
| Melting Point | 190-192℃ |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents. |
| Appearance | Yellow powder |
| Storage Condition | 2-8°C |
| MDL | MFCD11656140 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from dried nearly mature fruits of Evodia rutaecarpa. |
| In vitro study | Dehydroevodiamine (0-50 μM; 2 hours) inhibits iNOS and COX-2 expression and prevents degradation of IκB-α in LPS induced RAW 264.7 macrophages. Dehydroevodiamine (0-50 μM; 2 hours) inhibits a LPS-induced increase in the iNOS and COX-2 mRNA expression. Western Blot Analysis Cell Line: RAW 264.7 macrophage cells Concentration: 10 μM, 30 μM, 50 μM Incubation Time: pretreated 2 hours Result: Reduced iNOS and COX-2 expression and increased IκB-α expression. RT-PCR Cell Line: RAW 264.7 macrophage cells Concentration: 10 μM, 30 μM, 50 μM Incubation Time: pretreated 2 hours Result: Reduced iNOS and COX-2 mRNA expression. |
DEHYDROEVODIAMINE 去氢吴茱萸碱 - Reference
| Reference Show more | 1. Zhang Min Li Fei Dong Jiahao Wei feiting Liu Chao Yuan Jinbin. Simultaneous determination of four components in water extract of fructus evodiae by HPLC [J]. West China Pharmaceutical Journal 2018 33(05):523-525. 2. Xiao Yaohua, Lei Dandan, Xu Guobo et al. Simultaneous determination of seven components in Liangjiang Weiyang capsules by HPLC [J]. Chinese patent medicine 2019 041(008):1786-1790. 3. Li Fei, Dong Jiahao, Wei Fei, et al. Differences of components in different drug forms of fructus evodiae [J]. Chinese patent medicine 2019 041(010):2410-2414. 4. Dong Jiahao, Yuan Jinbin, Li Fei, et al. Influence of crushing and sieving conditions on determination results of fructus evodiae and its solution [J]. Chinese herbal medicine, 2018, 049(009):2026-2032. 5. Dong Jiahao, Li Fei, Wei feiting, etc. Optimization of extraction process of five active components from fructus evodiae by comprehensive evaluation method [J]. Jiangxi traditional Chinese medicine, 2017, 048(011):60-62. 6. Zhang Min, Dong Jiahao, Li Fei, et al. Simultaneous determination of four alkaloids in fructus evodiae alcohol extract by high performance liquid chromatography [J]. Medical leads, 2019(9). 7. Zhang Yuanyuan, Hu Yanzhen, Tian Yingying, et al. Separation of indole alkaloids by high performance liquid chromatography with ionic liquid as mobile phase additive [J]. Journal of Pharmaceutical Analysis, 2019, 039(011):2028-2033. 8. Xu Guobo, Lei Dandan, Xiao Yaohua, Chen Guanggui, He Xun, Liao Shanggao. Study on characteristic fingerprint of liangjiangweiyang capsule by HPLC [J]. Central South pharmacy, 2020,18(09):1503-1507. 9. [IF = 3.935] Xiaoshuang He et al."Screening of the active compound from tetranicarpum fruit and analysis of its binding characteristics to the α1A adrenoptor by high expression α1A adrenoptor cell." J Pharmaceut Biomed. 195: |
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View History
DEHYDROEVODIAMINE 去氢吴茱萸碱
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYL ESTER
2-(tert-Butyl) 7-ethyl 2,6-diazaspiro[3.4]octane-2,7-dicarboxylate
162327-73-3
Ethanone, 1-[3,3-difluoro-4-(3-hydroxy-1-azetidinyl)-1-piperidinyl]-2,2,2-trifluoro-
Benserazide impurity A(Secondary Standards traceble to EP)
(4-(氨基甲基)苯基)硼酸
Hydrazinium, 1,1,1-trimethyl-2-(3,3,5,5-tetramethylcyclohexylidene)-, tetrafluoroborate(1-) (1:1)
3H-Imidazo[4,5-c]pyridine, 2-(4-chloro-2-methoxyphenyl)-
N-(2-(4-[2-(TRIFLUOROMETHYL)-1,6-NAPHTHYRIDIN-5-YL]PIPERAZIN-1-YL)ETHYL)NICOTINAMIDE
(E)-(+/-)-2-AMINO-4-METHYL-5-PHOSPHONO-3-PENTENOIC ACID ETHYL ESTER
2-(tert-Butyl) 7-ethyl 2,6-diazaspiro[3.4]octane-2,7-dicarboxylate
162327-73-3
Ethanone, 1-[3,3-difluoro-4-(3-hydroxy-1-azetidinyl)-1-piperidinyl]-2,2,2-trifluoro-
Benserazide impurity A(Secondary Standards traceble to EP)
(4-(氨基甲基)苯基)硼酸
Hydrazinium, 1,1,1-trimethyl-2-(3,3,5,5-tetramethylcyclohexylidene)-, tetrafluoroborate(1-) (1:1)
3H-Imidazo[4,5-c]pyridine, 2-(4-chloro-2-methoxyphenyl)-
N-(2-(4-[2-(TRIFLUOROMETHYL)-1,6-NAPHTHYRIDIN-5-YL]PIPERAZIN-1-YL)ETHYL)NICOTINAMIDE